Fix envelope, tail usually is cranky with what you get away with as many samples have reverb on them. Make sure its nicely centered and not weird stereo image.
EQ hard on nice parts, into a dist, tame eq after, remove low and high end a bit. Works for all layers really, bottom, mid, highs. Can send this new channel and add final touches, no reverb though or similar.
Reverb after processing. Buss the reverb always for max control here you can do anything to it. Put it on mono left. Do same for a right channel clone reverb and work from there. Gives lot of control, no worries about disting or bitcrushing as it is mono.
You might want a low, mid and even high source if you really wanna control the space off it. EQ a lot on each part to get most off it.
Put it all in one channel and add some mild control fx, comp, focus eq. All this works well for short room reverb feel, don’t over do the reverb here.
You can have a long reverb on all of this now and put it on an own channel to mix with the more ambient side of the track.
If you sample is clean and well EQed to start with and you like as is. Just send it to reverb buss and put on a preset that works. Double up on this and treat bottom and highs separately.